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. 2019 Jul 10;13:316. doi: 10.3389/fncel.2019.00316

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Copyright © 2019 Gao, Zhang, Lu and Pei.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Elevation of mitochondrial membrane potential (MMP) in cells with transferred mitochondria (A–C) Measurement of MMP on co-cultured HA-GFP and HA-mitoBFP (A), HA-GFP and SK-mitoBFP (B), and Ast-GFP and hN-mitoBFP (C) by TMRE staining. TMRE signal intensity was compared between gated GFP⁺BFP⁺ and GFP⁺BFP^– cells. (D,E) Time-lapse live images showing the dynamics of mitochondria transferred from HA-mitodsred (D) or from SK-mitodsred (E) into HA-GFP along cell division. Data are represented as mean ± SEM. P values in A, B, C calculated with two-tailed student t test were <0.001. ^∗∗∗p < 0.001.