Table 2.

Antidepressants classes and single agents used with and without heart failure in the sample

Antidepressant classes and single agents	Total frequency (n=3799)	Percentage from all antidepressants used	With HF (n=410)	Percentage within HF	Without HF (n=3389)	Percentage within without HF	P* for Percentage HF and no HF
SSRI	1846	45.67	200	46.73	1646	45.55	0.917
Sertraline	663	16.40	67	15.65	596	16.49
Escitalopram	506	12.52	66	15.42	440	12.17
Citalopram	439	10.86	37	8.64	402	11.12
Paroxetine	122	3.02	11	2.57	111	3.07
Fluoxetine	87	2.15	15	3.50	72	1.99
Fluvoxamine	29	0.72	4	0.93	25	0.69
NaSSA	1121	27.73	123	28.74	998	27.61	0.180
Mirtazapine	1107	27.39	119	27.80	988	27.34
Mianserin	14	0.35	4	0.93	10	0.28
SNRI	641	15.86	60	14.02	581	16.08	0.285
Venlafaxine	287	7.10	27	6.31	260	7.19
Duloxetine	204	5.05	23	5.37	181	5.01
Desvenlafaxine	150	3.71	10	2.34	140	3.87
TCA	405	10.02	42	9.81	363	10.04	0.753
Amitriptyline	323	7.99	28	6.54	295	8.16
Dothiepin	30	0.74	3	0.70	27	0.75
Doxepin	26	0.64	3	0.70	23	0.64
Nortriptyline	23	0.57	7	1.64	16	0.44
Imipramine	2	0.05	1	0.23	1	0.03
Clomipramine	1	0.02	0	0	1	0.03
MAOI†	12	0.30	2	0.47	10	0.28	0.655
Others‡	17	0.42	1	0.23	16	0.44	0.593
Total	4042	100	428	100	3614	100	0.961

*Difference comparison P value based on Wilcoxon–Signed rank test, ^†The most commonly prescribed MAOI was moclobemide. Tranylcypromine was used once. ^‡Other prescribed antidepressants were agomelatine, reboxetine, and bupropion. The frequency was in respective order. HF=Heart failure, MAOI=Monoamine oxidase inhibitor, NaSSA=Noradrenaline and specific serotonergic antidepressant, SNRI=Serotonin norepinephrine reuptake inhibitor, SSRI=Selective serotonin reuptake inhibitor, TCA=Tricyclic antidepressant