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. 2019 Jul 1;2019:1351860. doi: 10.1155/2019/1351860

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Copyright © 2019 Shude Yang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The Potential of exosomes' ability to promote osteogenic differentiation of ADSCs. (a) qPCR analysis expression of osteogenesis-related genes (ALP, RUNX2) in NC, Exos_D0, Exos_D14, and PC on 7th day. (b) Semiquantitative analyses of ALP activity on 7th day. (c) Western blot analyses of the protein expression of ALP and RUNX2 on 14th day. (d) Relative intensity analyses of western blot results of ALP and RUNX2. (e) ARS staining on 21st day (1 represents NC, 2 represents Exos_D0, 3 represents Exos_D14, and 4 represents PC), scale bar: 100 μm. Notes: ^∗represents significant differences between NC and other groups; ^#represents significant differences between Exos_D14 and Exos_D0; NS represents no significant differences. ^∗ p < 0.05; ^# p < 0.05.