Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jul 10;13:293. doi: 10.3389/fncel.2019.00293

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Zong, Zhou, Ji, Jia, Tang and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Delayed clenbuterol treatment prevented the down-regulated CREB/BDNF signaling and reversed the decreased synaptic proteins. (A) Delayed clenbuterol administration prevented the down-regulated CREB/BDNF signaling. Representative Western blotting bands of pCREB, CREB, and mBDNF/proBDNF at 16 days following CLP in the hippocampus and quantitative analysis of the relative protein levels. (B) Clenbuterol ameliorated the decreased synaptic protein PSD95 and GluN2B induced by sepsis. Representative Western blots bands of PSD95, GluN2B and synaptophysin at 16 days following CLP and quantitative analysis of the relative protein levels. N = 3 mice/group. Compared with the CLP group, ^∗p < 0.05, ^∗∗p < 0.01, ^∗∗∗p < 0.001. All data are mean ± SEM.