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. 2019 Jul 1;2019:9096409. doi: 10.1155/2019/9096409

Table 1.

The concentrations of central neurotransmitters were determined by UFLC-MS/MS.

Analytes Control (ng/mL) Model (ng/mL) KXS (ng/mL) Hup A (ng/mL)
ACh 166.7 ± 21.8 99.0±10.0∗∗∗ 133.4 ± 10.6### 125.7 ± 7.6##
Tyr 7170 ± 897 4918±716∗∗∗ 5886 ± 608# 6407 ± 637##
DA 6.785 ± 1.678 2.673±0.773∗∗∗ 5.601 ± 1.383## 5.218 ± 0.965##
ME 10.76 ± 1.45 4.507±0.6441∗∗∗ 8.96 ± 1.10### 9.00 ± 0.72###
3-MT 1.821 ± 0.434 0.6645±0.3005∗∗∗ 1.505 ± 0.405## 1.425 ± 0.272##
Try 1.637 × 104 ± 0.332 × 104 1.580 × 104 ± 0.435 × 104 1.848 × 104 ± 0.465 × 104 1.763 × 104 ± 0.219 × 104
5-HTP 15.56 ± 3.96 4.144±0.985∗∗∗ 10.10 ± 3.38### 11.12 ± 1.38###
5-HT 959 ± 30 509.4±110.7∗∗∗ 787.9 ± 27.5### 719.1 ± 46.0###
5-HIAA 32.28 ± 2.80 5.864±0.847∗∗∗ 29.00 ± 1.43###$$$ 24.52 ± 2.33###
GABA 53.17 ± 7.05 37.02 ± 10.26 49.05 ± 9.19# 48.07 ± 7.34#

Data were expressed as the mean ± SD (n = 6). P < 0.05 and ∗∗∗ P < 0.001vs. the control group; # P < 0.05, ## P < 0.01, and ### P < 0.001vs. the model group; and $$$ P < 0.001vs. the Hup A group.