Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jul 9;12:5485–5497. doi: 10.2147/OTT.S197009

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 Ma et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

JAG1 was targeted by miR-34a-5p. (A) The putative binding regions of miR-34a-5p within the 3ʹUTR of JAG1 were predicted using miRTarBase and TargetScan online software. (B and C) Luciferase activity of JAG1 3ʹUTR-WT or JAG1 3ʹUTR-MUT reporter in DU145/DTX and PC3/DTX cells transfected with miR-NC or miR-34a-5p. (D and E) The protein levels of JAG1 in nontransfected or transfected DU145/DTX and PC3/DTX cells. *p<0.05.

Abbreviations: DTX, docetaxel; MUT, mutant; WT, wild type.