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. Author manuscript; available in PMC: 2019 Jul 17.
Published in final edited form as: Int J Pharm. 2017 Mar 24;523(1):310–319. doi: 10.1016/j.ijpharm.2017.03.039

Table 1.

Marketed ophthalmic ointment formulations[18–21]

No. Drug Product name Ointment base Applicant holder Treatment Year of approval
1 Bacitracin zinc; neomycin sulfate; polymyxin b sulfate Neomycin and Polymyxin B Sulfates and Bacitracin Zinc Ophthalmic Ointment, USP White petrolatum Akorn Superficial infections of the external eye 2004
2 Bacitracin zinc; hydrocortisone; neomycin sulfate; polymyxin b sulfate Neomycin and Polymyxin B Sulfates, Bacitracin Zinc and Hydrocortisone Ophthalmic Ointment, USP White petrolatum Akorn Steroid-responsive inflammatory ocular infection 2012
3 Oxytetracycline hydrochloride; polymyxin b sulfate Terramycin® White petrolatum, mineral oil Pfizer Superficial ocular infections (for animals) 1965
4 Bacitracin zinc; hydrocortisone; neomycin sulfate; polymyxin b sulfate Neomycin and Polymyxin B Sulfates, Bacitracin Zinc and Hydrocortisone Ophthalmic Ointment, USP White petrolatum, mineral oil Bausch & Lomb Steroid-responsive inflammatory ocular infection 1995
5 Bacitracin zinc; neomycin sulfate; polymyxin b sulfate Neomycin and Polymyxin B Sulfates and Bacitracin Zinc Ophthalmic Ointment USP White petrolatum, mineral oil Bausch & Lomb Superficial infections of the external eye 1995
6 Bacitracin zinc; neomycin sulfate; polymyxin b sulfate Neo-Polycin® White petrolatum, mineral oil Perrigo Superficial infections of the external eye 1981
7 Bacitracin zinc; polymyxin b sulfate AK-Poly-Bac™ White petrolatum, mineral oil Akorn Superficial infections of the external eye 1995
8 Bacitracin zinc; polymyxin b sulfate Bacitracin Zinc and Polymyxin B Sulfate Ophthalmic Ointment USP White petrolatum, mineral oil Bausch & Lomb Superficial infections of the external eye 1995
9 Bacitracin zinc; polymyxin b sulfate Polycin® White petrolatum, mineral oil Perrigo Superficial infections of the external eye 2002
10 Bacitracin zinc; hydrocortisone acetate; neomycin sulfate; polymyxin b sulfate Neo-Polycin® HC White petrolatum, mineral oil Perrigo Steroid-responsive inflammatory ocular infection 1981
11 Dexamethasone; neomycin sulfate; polymyxin b sulfate Neomycin and Polymycin B Sulfates and Dexamethasone Ophthalmic Ointment, USP White petrolatum, mineral oil Perrigo Steroid-responsive inflammatory ocular infection 1989
12 Erythromycin Erythromycin Ophthalmic Ointment USP White petrolatum, mineral oil Perrigo Superficial ocular infections 1983
13 Erythromycin Erythromycin Ophthalmic Ointment USP, 0.5% White petrolatum, mineral oil Akorn Superficial ocular infections 1996
14 Erythromycin Erythromycin Ophthalmic Ointment, USP 0.5% White petrolatum, mineral oil Bausch & Lomb Superficial ocular infections 1994
15 Ciprofloxacin hydrochloride Ciloxan® White petrolatum, mineral oil Novartis Bacterial conjunctivitis 1998
16 Dexamethasone; tobramycin TobraDex® White petrolatum, mineral oil Novartis Steroid-responsive inflammatory ocular infection 1988
17 Tobramycin Tobrex® White petrolatum, mineral oil Novartis External eye infection 1981
18 Gentamicin sulfate Gentak® White petrolatum, mineral oil Akorn Ocular bacterial infection 1995
19 Gentamicin sulfate Gentamicin Sulfate Ophthalmic Ointment, USP White petrolatum, mineral oil Perrigo Ocular bacterial infection 2004
20 Loteprednol etabonate Lotemax® White petrolatum, mineral oil Bausch & Lomb Post-operative inflammation and pain following ocular surgery 2011
21 Bacitracin Bacitracin Ophthalmic Ointment USP White petrolatum, mineral oil Perrigo Superficial ocular infections 1971
22 Sulfacetamide sodium Sulfacetamide Sodium Ophthalmic Ointment USP, 10% White petrolatum, mineral oil Perrigo Conjunctivitis and other superficial ocular infections 1971
23 Fluorometholone FML® mineral oil; petrolatum (and) lanolin alcohol; and white petrolatum. Allergan Corticosteroid-responsive inflammation 1985
24 Prednisolone acetate; sulfacetamide sodium BLEPHAMIDE S.O.P.® mineral oil; petrolatum and lanolin alcohol; and white petrolatum Allergan Steroid-responsive inflammatory ocular infection 1986
25 Dexamethasone; neomycin sulfate; polymyxin b sulfate Maxitrol® White petrolatum, anhydrous liquid lanolin Alcon Steroid-responsive inflammatory ocular infection 1963
26 Dexamethasone; neomycin sulfate; polymyxin b sulfate Neomycin and Polymyxin B Sulfates and Dexamethasone Ophthalmic Ointment, USP White petrolatum, mineral oil, lanolin Bausch & Lomb Steroid-responsive inflammatory ocular infection 1994
27 Gentamicin sulfate, prednisolone acetate PRED-G® Mineral Oil, petrolatum (and) lanolin alcohol, purified water, and white petrolatum Allergan Steroid-responsive inflammatory ocular infection 1989