Ceramics |
Ca-P based components |
HAp nanoparticles |
PCL; COL; CS; SF; cellulose; PLA; GEL; PLGA |
Major constituent of natural bone; promoting osteogenesis |
Finding proper proportion to improve mechanical properties |
Bottino et al., 2011; Wu et al., 2014; Lai et al., 2015; Tang et al., 2016; Ao et al., 2017
|
|
|
β-TCP |
PGS; PCL; CS |
Ideal resorbability; promoting osteogenesis |
Improving diameter, porosity, and contact angle |
Masoudi et al., 2017
|
|
Ca-Si based components |
BGs |
PCL; CS; GEL; COL; PVA |
Releasing Ca2+ ions and silicate; promoting osteogenesis |
Enhancing efficacy of osteogenesis activity |
Zhou et al., 2017b
|
|
Oxides |
ZnO |
PCL |
Antibacterial activity; promoting osteogenesis |
Ensuring non-toxicity |
Nasajpour et al., 2018
|
|
|
CaO |
PCL |
Promoting osteogenesis |
Improving mechanical properties |
Münchow et al., 2015b
|
Carbon-based components |
|
MWNTs |
PLGA; PLA |
Improving the strength and toughness; promoting osteogenesis |
Solving non-resorbability |
Zhang et al., 2018
|
|
|
GO |
P34HB |
Improving mechanical strength; antibacterial activity; promoting osteogenesis |
Solving non-resorbability |
Zhou et al., 2017a
|
Metal components |
|
AgNPs |
CS |
Excellent antibacterial activity |
Ensuring non-toxicity |
Shao et al., 2017
|
|
|
AuNPs |
/ |
Promoting osteogenesis |
Further exploring AuNPs incorporated nanofibers |
Jadhav et al., 2018
|
Drugs |
Antibiotics |
MNZ; ampicillin; amoxicillin; tetracycline hydrochloride; doxycycline hydrochloride; tinidazole |
PLA; PLGA; GEL; COL |
Ideal antibacterial activity |
Improving releasing profile |
Reise et al., 2012
|
|
NSAIDs |
Ibuprofen; piroxicam |
PCL; CS; PVA |
Anti-inflammation activity |
Improving releasing profile |
Batool et al., 2018
|
Growth factors |
|
BMP; PDGF |
COL |
Promoting osteogenesis |
Enhancing delivery efficacy and biological activity |
Ho et al., 2017
|
Proteins |
|
AMPs; |
PLGA; CS; GEL |
Antibacterial activity |
Guaranteeing biological activity |
He et al., 2018b
|
|
|
Fibronectin |
PLGA |
Enhancing cell recognition |
Improving connection method |
Campos et al., 2014
|