Table 2.
Multivariate model assessing change in MMSE scores as a function of study variables in repeated analysis from baseline to follow-up
| Estimate (95% CI) | |
|---|---|
| Time × alcohol consumption | |
| Baseline—non-drinkers | 0.12 (−0.38, 0.62) |
| Baseline—light to moderate drinker | 0.10 (−0.38, 0.59) |
| Baseline—heavy drinker | 0.05 (−0.52, 0.61) |
| Follow-up—non-drinkers | −0.71 (−1.21, −0.20) |
| Follow-up—light to moderate drinker | −0.31 (−0.80, 0.18) |
| Follow-up—heavy drinker | Reference |
| Age (≥75 years versus 65–74 years) | −0.58 (−0.72, −0.45) |
| Gender (women versus men) | 0.33 (0.19, 0.48) |
| Education (primary versus high school/college/university) | −0.74 (−0.94, −0.54) |
| Income (≥$55 000 versus < $55 000) | −1.41 (−1.81, −1.01) |
| Married (yes versus no) | 0.06 (−0.08, 0.20) |
| Area of residence (high versus low/medium deprivation) | −0.15 (−0.28, −0.02) |
| Social support (3 versus 0–2) | 0.49 (0.31, 0.67) |
| Daily hassles (3+ versus 0–2) | 0.03 (0.02, 0.05) |
| # of chronic physical disorders (≥3 versus 0–2) | 0.001 (−0.14, 0.14) |
| Functional status index (lowest quintile versus higher quintiles) | −0.24 (−0.41, −0.08) |
| Depression (yes versus no) | −0.17 (−0.47, 0.13) |
| Anxiety (yes versus no) | −0.26 (−0.47, −0.10) |
| Psychotropic drug use (yes versus no) | −0.11 (−0.31, 0.09) |
| Smoking status (never smoker versus past or current smoker) | −0.06 (−0.19, 0.08) |
| Exercise (# of time per week) | 0.01 (−0.003, 0.03) |
| # of ambulatory visits in past year | −0.004 (−0.01, 0.004) |
| Nested for type of primary care practice individuals were recruited in | |