Fig 5. Bar Chart showing fold change difference in fibrosis related gene expression to house keeping genes of adipose derived stem cell scleroderma fibroblast co-culture (ADSC-SSc Co Culture) versus scleroderma fibroblast monoculture (SSc mono).

[A] The majority of the fibrosis related genes were downregulated. The greatest fold change in expression was seen in genes marked with *including Matrix metalloproteinase-8 (MMMP-8), Platelet derived growth factor-β (PDGF-β) and Integrin Subunit Beta 6 (ITG-β6). Average fold change of co-culture versus monoculture of three independent experiments. Negative values = Decreased fold change in expression; Positive values = Increased fold change in expression.