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. 2019 Jul 17;14(7):e0219245. doi: 10.1371/journal.pone.0219245

Table 2. Association between toll-like receptor 1 (TLR1) immunoexpression and clinicopathological parameters (%).

TLR1 expression Strong Moderate Low or negative P value
N (%) 60 (39) 74 (48) 20 (13)
Age, years
< 65 13 (22) 19 (26) 11 (55) 0.016
≥ 65 47 (78) 55 (74) 9 (45)
Gender
Male 28 (47) 48 (65) 9 (45) 0.474
Female 32 (53) 26 (35) 11 (55)
Stage*
I 12 (20) 8 (11) 5 (25) 0.402
II 36 (60) 45 (61) 9 (45)
III 12 (20) 21 (28) 6 (30)
Lymph-node ratio
< 20% 47 (78) 57 (77) 14 (70) 0.476
≥ 20% 12 (20) 17 (23) 6 (30)
Missing data 1 (2) 0 (0) 0 (0)
Tumor size
≤ 30 mm 29 (48) 34 (46) 8 (40) 0.468
> 30 mm 28 (47) 38 (51) 12 (60)
Missing data 3 (5) 2 (3) 0 (0)
Perivascular invasion
Yes 14 (23) 21 (28) 8 (440) 0.222
No 35 (58) 38 (51) 10 (50)
Missing data 11 (18) 15 (20) 2 (10)
Perineural invasion
Yes 36 (60) 51 (69) 14 (70) 0.448
No 14 (23) 12 (16) 4 (20)
Missing data 10 (17) 11 (15) 2 (10)

Associations evaluated by Fisher’s exact test or linear-by-linear association test.

*Staging according to AJCC 8th edition.