Table 2. Summary of eFBAT-MM and SKAT-C analyses and results.
| eFBAT-MM | SKAT-C | |||
|---|---|---|---|---|
| CHOP-Trios | PCGC Trios | CHOP-CC1 | CHOP-CC2 | |
| Total variants | 5,578,860 | 6,812,971 | 5,601,587 | 5,601,152 |
| Rare variantsa | 3,446,735 | 4,502,285 | 3,502,419 | 3,495,988 |
| Number of genes | 21,256 | 22,247 | 21,212 | 21,269 |
| Genomic inflation factor (λ) | 1.03 | 1.04 | 1.09 | 1.09 |
| Genes with p<1E-03b | 13 | 13 | 25 | 27 |
|
CBLN2 C22orf39 NCOA2 CEP95 DDX5 SQRDL SLMO2-ATP5E TRIP13 PADI3 RBM47 PRR14 ZC3H18 CREBZF |
MIR518C GOLGA2P9 POU6F2 LCE4A TMEM206 LOC100996349 ASAH2 MBNL1 IGFBPL1 RNF44 IRAK2 DDX59 ADGRA3 |
FAM225A ABCB4 STK33 BLOC1S6 MIR3916 LEXM DACT3 MIR99AHG TRIP10 LINC00620 DACT3-AS1 NPPC GPATCH1 AVPR1A FLNC NCAPG SHD ARAP3 FIGN NCAN SYMPK MIR548AA2 MIR548D2 BHMG1 FCGR3B |
PSMG3 NEXN FUBP1 PSMG3-AS1 DNAJB4 TSSC4 TSPAN10 MKX-AS1 MKX UHMK1 ATG9B MMP19 CRTAM NPLOC4 GRID2 COPZ2 PTPRT PYGL COA5 EEF1B2 APOPT1 GATC ACTL7B NDUFS1 LOC101927653 AACS EPHB4 |
|
a Variants with minor allele frequency <0.05
b Genes are listed by p-value (lowest to highest). Specific p-values are provided in Tables B-E in S1 File.