Figure 4.
Effect of thermal denaturation of collagen on the T2 spectrum of bone (mean of each temperature with SD depicted in the shading). As the baking temperature increased, the T2 of the bound water pool shifted to higher values, while the distribution of T2 values within the pore water pool were seemingly unaffected (A). In the boiling and pressure‐heating experiment, the signals of the bound water pool shifted to higher T2 values, while the intensity of pore water pool signals at short‐T2's (>1 ms) increased (B). At the highest temperature, the bound and pore water pools mixed.