FIG. 1.

Identification, screening, and selection of articles reporting endometrial histology in menopausal women using vaginal estrogens. ^aMeeting abstracts from a search of major women's health meetings in the past 5 years for studies that were not found in the literature search results. ^bVaginal ring with progestin included studies of vaginal rings resulting in systemic levels of estrogen to treat vasomotor symptoms so that a progestin had to be given. ^cOne article was published in 1979 and did not mention endometrial data in the abstract, and the other was published in 1963 with no abstract available. ^dMeeting abstracts with a full publication, with no endometrial data, or not relevant. ^eDoes not include estriol studies; comparative studies with estriol were included, but only data for other vaginal estrogens were summarized.