TABLE 1.
Identified mutations in genes other than katG in INH-resistant M. tuberculosis strainsa
| oxyR’-ahpC intergenic region | furA-katG intergenic region | Ndh |
| t-89a (130) | c-1 ins (102) | R13C (67) |
| g-88a (130) | g-7a (96) | V18A* (66–67) |
| c-81t (131) | a-10c (96) | T110A (68) |
| g-74a (132) | g-12a (96) | R268H (66, 68) |
| c-72t (131) | G313R* (116) | |
| g-67a (66) | fabG-inhA regulatory region | |
| g-66a (133) | g-147t (88) | iniB |
| atgt-54 ins (92) | a-113c (134) | t198ins (135) |
| c-54t (132) | g-102a (134) | a211del (135) |
| c-52t (136) | a-92t (69) | 222 12bp del (88) |
| g-51a (131) | g-67c (137) | N88S* (116) |
| t-49g (137) | g-47c,a (134, 138) | G192* (135) |
| g-48a (135, 139) | c-34t (138) | H481Q* (116) |
| g-46a* (102, 140) | t-24g (141) | |
| g-46 del* (66) | g-22c (142) | iniA |
| c-45t (84) | g-17t* (66, 135, 139, 143) | P3A (88) |
| t-44a (99) | a-16g (84) | nt282–286 del (88) |
| t-40c (144) | c-15t (66, 88, 135, 139, 140, 143) | H481Q* (88, 135) |
| c-39t (66, 135, 139, 140, 144) | t-12a (145) | R537H (88, 135) |
| t-34c,a (102, 140) | a-11t (66) | |
| t34 del (102) | t-8a*,g,c (66, 88, 140–142) | iniC |
| g-32a (140) | t-5a (146) | t79ins (135) |
| c-30t (66, 144) | c-4a (140) | a98ins (135) |
| c-20t* (102) | A5P (137) | W83G (88) |
| c-15t (66, 135, 139, 144) | V14L (137) | |
| c-12t (66, 135, 139, 140) | T21A (66) | Rv0340 |
| c-10a,g,t (66, 135, 139, 140) | T143* (135) | |
| g-9a* (66, 135, 139, 140, 144) | inhA ORF | G149* (135) |
| g-6a (66, 140, 144) | M1L (147) | V163I (88, 135) |
| a-4g (140) | K8N (148) | |
| I16T (149) | nat | |
| ahpC ORF | I21T,V (66, 88, 135, 139, 149) | G67R* (88) |
| P2S (69) | I25T (136) | Y177H (150) |
| L3K (140) | I47T* (66,149) | G207R* (88, 103) |
| L4R (130) | V78A (149) | |
| T5I (66) | S94A (59, 66,144) | Rv1592c |
| F10I (144) | I95P (151) | P42L (88) |
| D33N (84) | A190S (152) | V430A (88) |
| D73H* (66) | I194T* (66, 88) | |
| E76K (153) | R202G (133) | fadE24 |
| L191K (66) | E217D (133) | -64 2 bp ins (88) |
| T241M (142) | a-23c* (88) | |
| oxyR’ | T253A* (152) | |
| G12a (130) | D256N (152) | Rv1772 |
| g18a (69) | I258T,V (135, 152) | T4A (88) |
| g27t (69) | Y259H (152) | |
| c28a (69) | efpA | |
| c37t (99) | kasA | T15R* (116) |
| bp67 ins ggcg (99) | D66N* (66, 109) | I73T* (135) |
| g325t (99) | M77I* (88, 135) | Q513R (116) |
| a331c (99) | R121K (69) L245R (135) | E520V (135) |
| furA | G269S* (66, 69, 88, 109, 135,139) | fabD |
| S5P (88, 135) | G312S* (66, 69, 109, 135) | S275N* (88) |
| c34 del (96) | S341* (135) | A199T* (88) |
| A14V (96) | G387D (69) | |
| A46V* (116) | F413L (109) | accD6 |
| L68F (94) | D229G* (88) | |
| C97Y (94) | srmR homolog | |
| D3G (88) | fbpC | |
| M323T* (88) | G158S* (88) |
a
Asterisk (*), found in INH-resistant and/or INH-sensitive strains.