Table 2. Dosage forms and main components of film forming systems.
Dosage Form | Active Ingredient | Polymer | Solvent | Refs. |
---|---|---|---|---|
- | Betamethasone valerate | Klucel™ LF; Kollidon® 12 PF/17 PF/25/30; EC; CH; PAMA+; PME; PAOC | Ethanol | [54] |
Betamethasone valerate | HPC, PAMA+, PAOC | Ethanol | [52] | |
Betamethasone valerate | HPC, PAMA+, PAOC | Ethanol | [53] | |
Ethinylestradiol | PAMA+, HPC, PU | Ethanol or ethanol/water | [56] | |
Flurbiprofen Ketoprofen Ibuprofen |
PAMA+ | Isopropyl alcohol/acetone | [32] | |
Ketorolac | PAMA+, Eudragit E, PVP K30 | Ethanol | [57] | |
Mupirocin | PAMA | Ethanol/acetone | [58] | |
Oxybutynine | Carbopol 940, Lutrol F127 | Ethanol/acetone/methylal | [59] | |
Metered dose spray | Methylphenidate | PAMA, PAMA+ | Ethanol; isopropyl alcohol | [60] |
Ropivacaine | PAMA+, PAMA, PAA, HPC, polaxamer, PVA, PVP |
Ethanol; isopropyl alcohol | [61] | |
Betamethasone valerate | PVP K90 | Ethanol | [62] | |
Testosterono | PAMA+, Eudragit E, PVPS630, PVP K30 | Ethanol | [41] | |
Dexketoprofen | PAMA+, PVP K12, PVPS630, PVP K30 | Ethanol | [63] | |
Fluconazole | EC, PAMA+ | Alcohol-acetone | [64] | |
Lotion | Testosterone | PVP | Isopropyl alcohol | [65] |
Emulsion | Nonivamide | Water | [66] | |
Nonivamide | PAMA+ | Water | [67] | |
Nonivamide | PME, PAMA+ | Water | [68] | |
Gel | -- | PVA | Water | [69] |
Caffeine | Fibroin | Water/ethanol | [44] | |
Ketoprofen | CH | Water/ethyl alcohol | [70] | |
Rotigotine | HPC and Carbomer 934 | Water/ethanol | [71] | |
Tolterodine | Carbopol 980 (neutralized by triethanolamine), HPC, HPMC | Water/ethyl alcohol | [72] |
Abbreviations: PAMA+ poly(ammoniummethyl methacrylate) (Eudragit®RL or Eudragit®RS); PAMA poly(aminomethyl methacrylate) (Eudragit®E); PAA poly(methylmethacrylic acid) (Eudragit®L); HPC hydroxypropyl cellulose; polaxamer; PVA poly vinyl alcohol; PME polymethylethylacrylate (Eudragit NE); PVP polyvinyl pyrrolidone; EC ethyl cellulose; CH chitosan; HPCH hydroxypropyl chitosan; PAOC Acrylates/Octylacrylamide Copolymer (Dermacryl 79); PU polyurethane; HPMC hydroxypropyl methyl cellulose.