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. 2019 Jul 17;10:3042. doi: 10.1038/s41467-019-10759-z

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — TCER-1-repressed genes are essential for resistance against PA14. Survival of wild-type L4 animals grown from egg stage on empty control vector (black, WT/Ctrl) or tcer-1 RNAi bacteria (blue, WT/tcer-1) and then transferred to PA14 plates compared to the survival of a dod-3, b irg-5, c dod-24 or d ilys-3 mutants grown on empty control vector (pink curves) or tcer-1 RNAi bacteria (red). a WT/Ctrl (m = 87.63 ± 2.2), WT/tcer-1 (m = 99.27 ± 2.1), dod-3/Ctrl (m = 79.95 ± 1.5), dod-3/tcer-1 (m = 78.8 ± 1.4). b WT/Ctrl (m = 77.67 ± 3.0), WT/tcer-1 (m = 104.62 ± 2.7), irg-5/Ctrl (m = 53.07 ± 0.7), irg-5/tcer-1 (m = 56.69 ± 1.2). c WT/Ctrl (m = 87.63 ± 2.2), WT/tcer-1 (m = 99.27 ± 2.1), dod-24/Ctrl (m = 66.18 ± 1.4), dod-24/tcer-1 (m = 74.20 ± 1.5). d WT/Ctrl (m = 72.12 ± 2.3), WT/tcer-1 (m = 81.33 ± 2.5), ilys-3/Ctrl (m = 52.15 ± 1.9), ilys-3/tcer-1 (m = 55.21 ± 2.0). e Survival of wild type and mutants transferred to PA14 plates at L4 stage. WT (black, m = 88.05 ± 2.0), tcer-1 (blue, m = 111.81 ± 2.3), ilys-3 (pink, m = 54.29 ± 1.3) and tcer-1;ilys-3 (m = 60.74 ± 1.5). f WT (m = 60.06 ± 0.8), tcer-1 (m = 87.9 ± 2.0), dod-3 (m = 70.87 ± 0.75) and tcer-1;dod-3 (m = 79.06 ± 1.3). Survival estimated using the Kaplan−Meier analysis and shown as mean lifespan in hours (m) ± standard error of the mean (SEM). P values were adjusted for multiplicity where applicable. Asterisks indicate statistical significance <0.01 (**), <0.001 (***) and <0.0001 (****) and their color denotes the strain of comparison. Assays in panels (a) and (c) were performed in the same biological replicate so their controls are shared. Details of number of animals and data from additional trials are presented in Supplementary Table 6