Figure 2.

UDCA promotes bile acid synthesis, especially in the alternative pathway and induces the expression of bile acid transporter genes and proteins in the ileum. (a) Diagram and mRNA analysis of bile acid biosynthesis markers in the liver (n = 6 per group). (b) Diagram and mRNA analysis of bile acid transporters in the ileum (n = 6 per group). (c) Protein expression levels of bile acid transporters in the ileum and densities of protein levels relative to β‐actin shown as fold change relative to the control group (n = 6 per group). (d) Representative pictures of immunohistochemistry of bile acid transporter proteins in the ileum and integrated option density shown as a bar chart (n = 6 per group). Mean values ± SEM are expressed for the bar chart. *P < .05 versus normal control group