Table 1.
Selected peptides with mutated sequences.
| Sequence | UniProt ID | Protein Name | Mutation | Cells line presence | Pfam Domain |
|---|---|---|---|---|---|
| AFQHLSEAVQAAEEEAQPPSWSCGLAAGVIDAYMTLADFCDQQLR | P78527 | DNA-dependent protein kinase catalytic subunit | P3405L | MCF10 | FAT |
| AGNVSKDEIDSAVKMLVSLK | P23381 | Tryptophan–tRNA ligase, cytoplasmic | A31V | MCF10 | WHEP-TRS |
| AINQSQSVQESLESLLQSIGEVEQNLEGK | Q9UPN3-5 | Isoform 4 of Microtubule-actin cross-linking factor 1 | A2547? | MCF10 | |
| ALMLQGVDLLDDAVAVTMGPK | C9JL25 | 60 kDa heat shock protein, mitochondrial (Fragment) | A90D | MCF7, MCF10, SKBR3 | Cpn60 TCP1 |
| AMQAAGQIPATALLPTMTPDGLSVTPTPVPVVGSQMTR | P26368 | Splicing factor U2AF 65 kDa subunit | A131S | MCF7 | |
| ASTVKSVLELIPELNEKGEAYNSLMK | P42704 | Leu-rich PPR motif-containing protein, mitochondrial | E1318G | MCF7, MCF10 | |
| CAPLFSGTEHHASLIDSLLHTVYRLSK | Q92736 | Ryanodine receptor 2 | A2536S | MCF7 | |
| CQEKWDKLLLTSTEK | Q7L0Y3 | Mitochondrial ribonuclease P protein 1 | Y262C | MCF7, MCF10 | tRNA m1G MT |
| DDLQFLADLEELITKFQVFRISQR | Q9Y6X0 | SET-binding protein | H971Q | MCF7, MCF10, SKBR3 | |
| DIMTYVSSFYHAFSGAQK | O43707 | Alpha-actinin-4 | A256D | MCF7, MCF10 | CH |
| DQEGQDLLLFIDNIFR | P06576 | ATP synthase subunit beta, mitochondrial | V301L | SKBR3 | ATP-synt ab |
| EAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYMSQFPK | P21333 | Filamin-A | L261M | MCF7, MCF10 | CH |
| EAVMSFSITETEKIK | Q5T4T6 | Synaptonemal complex protein 2-like | N353S | MCF10 | |
| EFADSLGIPFLETSAKNAMNVEQSFMTMAAEIK | P62820 | Ras-related protein Rab-1A | T159M | SKBR3, MCF7 | Ras |
| EFDTLSGKVEESPDK | Q9BXX2 | Ankyrin repeat domain-containing protein 30B | L760V | SKBR3 | |
| EIYPYVIQERRPTLNELGISTPEELGLDKV | P20674 | Cytochrome c oxidase subunit 5 A, mitochondrial | L130R | SKBR3, MCF7 | COX5A |
| EQLQQEQALLEEIER | Q15149 | Plectin | R1386Q | SKBR3, MCF7 | |
| FGLAHLMALGLGPWMAVEIPDLIQK | Q9Y3C8 | Ubiquitin-fold modifier-conjugating enzyme 1 | L146M | MCF10 | UFC1 |
| FQSSAVMALQEGCEAYLVGLFEDTNLCAIHAK | P68431 | Histone H3.1 | A96G | SKBR3, MCF10 | Histone |
| FTLDCTHPVEDGIMDAANYEQFLQER | P35268 | 60 S ribosomal protein L22 | 39Y | SKBR3, MCF10 | Ribosomal L22e |
| GCIEKLSEDVEQLKK | P61266 | Syntaxin-1B | V53L | MCF7 | Syntaxin |
| GFDFVTFESPADAK | P38159-3 | Isoform 3 of RNA-binding motif protein, X chr | A52D | MCF10 | RRM 1 |
| GFGFITFTNPEHASDAMR | P98179 | Putative RNA-binding protein 3 | V62D | MCF7 | RRM 1 |
| GMLDLLEVHLLDFPNIVIK | Q6P2Q9 | Pre-mRNA-processing-splicing factor 8 | P1871L | MCF7 | PRP8 domainIV |
| GTAAAAAAAAAAAAAK (insertion in frame) | P50914 | 60 S ribosomal protein L14 | A159_K160insAAA | MCF7, MCF10 | |
| HQGVMVGMCQKDSYVGDEAQSK | P68133 | Actin, alpha skeletal muscle | G50C | MCF7, MCF10, SKBR3 | Actin |
| HRILPEKYPPPTELLDLQPLPVSALR | O75643 | U5 small nuclear ribonucleoprotein 200 kDa helicase | L1289R | MCF7 | |
| IMSLVDPNHCGLVTFQAFIDFMSR | O43707 | Alpha-actinin-4 | S823C | SKBR3, MCF7 | |
| KHTLSFVDVGTGK | P31040 | Ubiquinone flavoprotein subunit, mitochondrial | Y629F | MCF7 | Succ DH flav C |
| KSQESLTENPSETLKPATSISSTSQTKGINVK | F5GXV7 | Neurobeachin | I1735T | MCF10 | |
| LCGLLVLGSWCISVMGFLLETLTILR | O60412 | Olfactory receptor 7C2 | S156F | MCF10 | 7tm 4 |
| LCYVALYFEQEMATAASSSSLEK | Q6S8J3 | POTE ankyrin domain family member E | D922Y | MCF7 | Actin |
| LDTNSDGQLDYSEFLNLIGGLAMACHDSFLK | P31949 | Protein S100-A11 | F77Y | MCF10 | EF-hand 1 |
| LFDHLESPTPNPTEPLFLAQAEVYK | P49327 | Fatty acid synthase | P972L | SKBR3 | PS-DH |
| LFLASLAAAGSGTDAQVALENEVK | Q7Z6Z7 | E3 ubiquitin-protein ligase HUWE1 | V2153E | SKBR3 | |
| LTENLSALQR | Q8TD16-2 | Isoform 2 of Protein bicaudal D homolog 2 | R398Q | MCF7 | BicD |
| LTQAQIFDYSEIPNFPR | P00491 | Purine nucleoside phosphorylase | G51S | MCF7 | PNP UDP 1 |
| MDATFIGNSTAIQELFK | P04350 | Tubulin beta-4A chain | A364D | MCF7, MCF10, SKBR3 | Tubulin C |
| MHDMNTDQENLVGTHDAPIR | O43684 | Mitotic checkpoint protein BUB3 | L84M | MCF7 | |
| MLVVLRQGTREEDDVVSEDLVQQDVQDLYEAGELK | P08133 | Annexin A6 | L162R | SKBR3 | |
| QVHPDTGISSKVMGIMNSFVNDIFER | P23527 | Histone H2B type 1-O | A59V | SKBR3, MCF7 | Histone |
| QVYPDTGISSKAMGIMNSFVNDIFER | O60814 | Histone H2B type 1-K | H50Y | SKBR3, MCF7 | Histone |
| SDASSGQSGSRSASRTTR | P20930 | Filaggrin | R884S | SKBR3 | |
| SLGQNPTEAELQDMINEVDADGNGTIDFPEFFTMMAR | P62158 | Calmodulin | L70F | MCF7, MCF10, SKBR3 | EF-hand 7 |
| SMGIMNSFVNDIFER | Q8N257 | Histone H2B type 3-B | A59S | MCF7, MCF10, SKBR3 | Histone |
| SVIVVLRLNVDLQAVVIFELVY (del/frame shift) | Q8TC27 | Disintegrin and metalloproteinase domain protein 32 | K388fs*39 | SKBR3, MCF7 | |
| SYELPDGQVITIGKER | P68133 | Actin, alpha skeletal muscle | N254K | MCF7, MCF10, SKBR3 | Actin |
| TSPDPLPVSAAPSKAGLPR | Q13469 | Nuclear factor of activated T-cells, cytoplasmic 2 | S330L | MCF7 | |
| TTGIVMDSGDGVTHTVPIYEAYALPHAILR | P63261 | Actin, cytoplasmic 2 | G168A | MCF7, MCF10, SKBR3 | Actin |
| TVSLGAGSKDELHIVEAEAMNYEGSPIK | P06748-3 | Isoform 3 of Nucleophosmin | A53S | SKBR3, MCF10 | Nucleoplasmin |
| VSELEEFINGPNNAHIQQVGDR | P53675 | Clathrin heavy chain 2 | D1188E | MCF10 | Clathrin |
| VTNGAFTGEISLGMIK | P60174-1 | Isoform 2 of Triosephosphate isomerase | P81L | SKBR3, MCF7 | TIM |