Table 1.
Patient characteristics of CTC subpopulation and overall CONVERT population
| CTC subpopulation |
Overall population |
|||||
|---|---|---|---|---|---|---|
| N | % | Arm 1 | Arm 2 | Arm 1 | Arm 2 | |
| No. patients | 75 | 100 | 39 | 36 | 273 | 274 |
| Age at baseline, years, median (range) | 62.7 | 65.8 | 61.6 | 63.8 | 62.5 | |
| (77.1–45.1) | (51.5–77.1) | (45.1–76.8) | (34.2–81.6) | (29.7–84.3) | ||
| Sex | ||||||
| Female | 40 | 53 | 20 (51%) | 20 (56%) | 123 (45%) | 127 (46%) |
| Male | 35 | 47 | 19 (49%) | 16 (44%) | 150 (55%) | 147 (54%) |
| TNM group | ||||||
| Group 1: I–II | 11 | 15 | 7 (18%) | 4 (11%) | 51 (19%) | 35 (13%) |
| Group 2: III | 61 | 81 | 30 (77%) | 31 (86%) | 207 (76%) | 219 (80%) |
| ECOG PS | ||||||
| 0 | 22 | 29 | 12 (31%) | 10 (28%) | 123 (45%) | 125 (46%) |
| 1 | 49 | 65 | 25 (64%) | 24 (67%) | 142 (52%) | 137 (50%) |
| 2 | 4 | 5 | 2 (5%) | 2 (6%) | 8 (3%) | 9 (3%) |
| PET | ||||||
| Staged | 27 | 36 | 14 (39%) | 13 (33%) | 157 (57%) | 155 (57%) |
| Non-staged | 48 | 64 | 22 (61%) | 26 (67%) | 113 (41%) | 118 (43%) |
| CTC count, median (range) | 1 (0–3750) | |||||
| Per arm, median (range) | 1 (0–164) | 1 (0–3750) | ||||
CTC, circulating tumour cell; TNM, tumour node metastasis; ECOG PS, Eastern Cooperative Oncology Group Performance Status; PET, positron emission tomography.