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. Author manuscript; available in PMC: 2019 Jul 18.
Published in final edited form as: Nanomedicine. 2017 Jan 4;13(3):1137–1146. doi: 10.1016/j.nano.2016.12.018

Figure 3.

Figure 3

Nanoparticle immunostimulatory activity. Human astrocyte-like and microglia-like cell lines were transfected with NPs at a final concentration of 5 nM and 20 nM. Cell supernatants were collected at 24 h post transfection and levels of IFN-β and IL-1β assessed by specific-capture ELISA. Differences in inflammatory mediator release between cells transfected with NPs and the L2K control were compared with Student’s two-tailed t test. Asterisks indicate a statistically significant differences (P value <0.05).