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. Author manuscript; available in PMC: 2020 Mar 5.
Published in final edited form as: ChemMedChem. 2019 Feb 5;14(5):545–560. doi: 10.1002/cmdc.201800725

Figure 5.

Figure 5.

Inhibition of BACE2 processing of Tmem27 by CpdJ and compound 2a (at two different concentrations) in MIN6 cells. Lanes 1 and 5 represent vehicle (DMSO) controls with and without DAPT, respectively.