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. 2019 Jul 17;17:228. doi: 10.1186/s12967-019-1969-1

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Characteristics of the microbial community composition in the CKD5-HD and healthy control groups. a The major differentially abundant taxa between CKD5-HD and healthy control subjects (LDA score above 3.0), which was generated from LEfSe analysis. b The enriched taxa in the CKD5-HD and healthy control gut microbiomes are represented in the cladogram. The central point represents the root of the tree (bacteria), and each ring represents the next lower taxonomic level (order to genus: D_3 order, D_4 family, D_5 genus). The diameter of each circle represents the relative abundance of the taxon. c–e Relative abundance of taxa between the CKD5-HD and healthy control subjects was compared (Mann–Whitney U test). H CKD5-HD group, N normal group