Table 1.
Baseline characteristics of type 2 diabetic patients with or without NAFLD
Men | Women | |||||
---|---|---|---|---|---|---|
NAFLD(−) | NAFLD(+) | P | NAFLD(−) | NAFLD(+) | P | |
N | 147 | 89 | – | 113 | 96 | – |
Age, years | 57.6 ± 9.4 | 59.4 ± 9.8 | 0.169 | 61.1 ± 9.3 | 61.4 ± 8.7 | 0.834 |
Duration of diabetes, years | 8.0 ± 7.1 | 6.1 ± 6.1 | 0.040 | 9.1 ± 6.6 | 7.7 ± 6.7 | 0.143 |
Duration of hypertension, years | 3.1 ± 5.6 | 5.5 ± 7.1 | 0.05 | 5.0 ± 6.7 | 6.9 ± 7.0 | 0.045 |
Height, cm | 167.9 ± 5.7 | 167.5 ± 5.1 | 0.596 | 154.9 ± 5.7 | 155.9 ± 5.7 | 0.201 |
Weight, cm | 65.0 ± 9.1 | 73.6 ± 10.2 | < 0.001 | 58.3 ± 9.1 | 63.3 ± 11.7 | 0.001 |
Body mass index, Kg/m2 | 23.0 ± 2.9 | 26.2 ± 3.4 | < 0.01 | 24.3 ± 3.5 | 26.0 ± 4.4 | 0.002 |
Waist circumference, cm | 85.6 ± 8.5 | 94.7 ± 8.4 | < 0.001 | 86.8 ± 11.8 | 92.2 ± 11.4 | 0.001 |
Systolic blood pressure, mmHg | 133.2 ± 21.8 | 138.4 ± 20.6 | 0.069 | 145.7 ± 26.4 | 140.8 ± 19.3 | 0.133 |
Diastolic blood pressure, mmHg | 76.0 ± 12.5 | 80.7 ± 12.4 | 0.005 | 75.7 ± 12.8 | 76.8 ± 12.6 | 0.529 |
Hemoglobin A1c, mmol/L | 10.3 ± 2.8 | 9.6 ± 2.2 | 0.005 | 9.4 ± 2.0 | 9.4 ± 2.1 | 0.901 |
Total cholesterol, mmol/L | 4.2 ± 1.1 | 4.6 ± 1.3 | 0.016 | 4.6 ± 1.4 | 4.9 ± 1.4 | 0.050 |
Triglycerides, mmol/L | 1.4 ± 0.9 | 2.3 ± 2.2 | < 0.001 | 1.9 ± 2.1 | 2.3 ± 1.8 | 0.155 |
HDL-cholesterol, mmol/L | 1.0 ± 0.3 | 0.9 ± 0.2 | 0.152 | 1.1 ± 0.3 | 1.0 ± 0.2 | 0.390 |
LDL-cholesterol, mmol/L | 2.5 ± 0.9 | 2.6 ± 1.0 | 0.201 | 2.6 ± 0.9 | 2.8 ± 0.9 | 0.061 |
ALT, IU/L | 24.2 ± 14.5 | 28.5 ± 18.2 | 0.047 | 20.8 ± 11.8 | 25.0 ± 14.0 | 0.039 |
AST, IU/L | 22.6 ± 10.5 | 25.4 ± 11.5 | 0.054 | 22.1 ± 9.7 | 25.0 ± 11.2 | 0.049 |
Current smoking, % | 44.2 | 43.8 | 1.000 | 1.8 | 0 | 0.501 |
Current drinking, % | 10.2 | 11.2 | 0.829 | 0 | 0 | 1.000 |
Menopause, % | – | – | – | 89.2 | 91.3 | 0.645 |
Medications | ||||||
Statin (%) | 8.2 | 11.1 | 0.717 | 10.4 | 8.3 | 1.000 |
Metformin (%) | 53.1 | 61.1 | 0.512 | 50.0 | 61.1 | 0.378 |
Insulin (%) | 65.3 | 50.0 | 0.185 | 70.8 | 63.9 | 0.637 |
ASM, kg | 21.5 ± 2.8 | 22.6 ± 2.7 | 0.002 | 15.4 ± 2.4 | 15.7 ± 2.6 | 0.369 |
Visceral fat area, cm2 | 95.7 ± 25.6 | 120.7 ± 36.0 | < 0.001 | 104.7 ± 32.9 | 121.0 ± 28.8 | < 0.001 |
SVR, g/cm2 | 238.7 ± 73.3 | 197.8 ± 57.4 | < 0.001 | 160.0 ± 58.0 | 136.7 ± 38.1 | 0.001 |