Table 2.
Correlations the clinical characteristics among CNR1 between HCC with or without cirrhosis in TCGA
| Variables | N | Non-cirrhotic HCC | N | Cirrhotic HCC | ||
|---|---|---|---|---|---|---|
| CNR1 | CNR1 | |||||
| Low/high expression case (n) | p value | Low/high expression case (n) | p value | |||
| Gender | ||||||
| Male | 82 | 44/38 | 0.282 | 61 | 31/30 | 0.635 |
| Female | 50 | 22/28 | 18 | 8/10 | ||
| Age at diagnosis | ||||||
| ≥ 60 | 80 | 38/42 | 0.476 | 36 | 17/19 | 0.650 |
| < 60 | 52 | 28/24 | 42 | 22/20 | ||
| NA | 0 | 0 | 1 | 0/1 | ||
| T stage | ||||||
| T1/T2 | 97 | 48/49 | 1.000 | 70 | 35/35 | 0.712 |
| T3/T4 | 33 | 17/16 | 8 | 3/5 | ||
| TX | 1 | 1/0 | 0 | 0/0 | ||
| NA | 1 | 0/1 | 1 | 1/0 | ||
| N stage | ||||||
| N0 | 91 | 49/42 | 0.259 | 57 | 29/28 | 1.000 |
| N1 | 1 | 0/1 | 1 | 0/1 | ||
| NX | 40 | 17/23 | 20 | 10/10 | ||
| NA | 0 | 0/0 | 1 | 0/1 | ||
| M stage | ||||||
| M0 | 90 | 46/44 | 0.529 | 62 | 31/31 | 0.830 |
| M1 | 4 | 3/1 | 0 | 0/0 | ||
| MX | 38 | 17/21 | 17 | 8/9 | ||
| Pathologic stage | ||||||
| I/II | 91 | 44/47 | 0.755 | 67 | 35/32 | 0.478 |
| III/IV | 33 | 17/16 | 9 | 3/6 | ||
| NA | 8 | 5/3 | 3 | 1/2 | ||
| Vascular invasion | ||||||
| None | 87 | 38/49 | 0.127 | 52 | 26/26 | 0.900 |
| Micro | 33 | 18/15 | 22 | 10/12 | ||
| Macro | 6 | 5/1 | 2 | 1/1 | ||
| NA | 6 | 5/1 | 3 | 2/1 | ||
| HBV infection | ||||||
| Yes | 38 | 25/13 | 0.036 | 36 | 20/16 | 0.358 |
| No | 88 | 40/48 | 40 | 18/22 | ||
| NA | 6 | 1/5 | 3 | 1/2 | ||
| HCV infection | ||||||
| Yes | 14 | 6/8 | 0.488 | 20 | 13/7 | 0.118 |
| No | 112 | 59/53 | 56 | 25/31 | ||
| NA | 6 | 1/5 | 3 | 1/2 | ||
NA not applicable
The significant p value is marked with italic type