Table 1.
Comparison of related indexes before and after menopause in the general population
| Total population | Z/χ2 | P | ||
|---|---|---|---|---|
| Premenopausal (n = 207) |
Postmenopausal (n = 3020) |
|||
| Age (years) | 46.65 ± 1.78 | 60.61 ± 7.55 | −75.59 | < 0.001 |
| BMI (kg/m2) | 24.01 (22.19, 25.86) | 24.46 (22.43, 26.67) | −1.94 | 0.05 |
| WC (cm) | 78 (73, 81) | 81 (78, 88) | −7.43 | < 0.001 |
| SBP (mmHg) | 128 (120, 138) | 135 (124, 150) | −6.31 | < 0.001 |
| DBP (mmHg) | 79 (71, 86) | 82 (75, 90) | −3.66 | < 0.001 |
| HbA1c (%) | 5.4 (5.1, 5.8) | 5.7 (5.4, 6) | −6.25 | < 0.001 |
| FPG (mmol/L) | 5.19 (4.89, 5.53) | 5.46 (5.11, 5.98) | −6.62 | < 0.001 |
| TC (mmol/L) | 4.72 (4.21, 5.38) | 5.24 (4.67, 5.82) | −7.60 | < 0.001 |
| TG (mmol/L) | 1.48 (1.12, 2.01) | 1.77 (1.39, 2.35) | −6.04 | < 0.001 |
| LDL-C (mmol/L) | 2.44 (2.07, 2.76) | 2.74 (2.3, 3.2) | −6.53 | < 0.001 |
| HDL-C (mmol/L) | 1.4 (1.21, 1.6) | 1.37 (1.18, 1.59) | −0.71 | 0.48 |
| CREA (μmol/L) | 57.7 (53.4, 64.3) | 61.5 (54.9, 68.8) | −4.14 | < 0.001 |
| UA (μmol/L) | 234.2 (201.7, 267.1) | 252.9 (214.13, 298.78) | −4.82 | < 0.001 |
| BUN (mg/dl) | 4.43 (3.74, 5.29) | 4.95 (4.24, 5.8) | −5.81 | < 0.001 |
| ALT (U/L) | 18 (14, 25) | 20 (16, 26) | −4.27 | < 0.001 |
| AST (U/L) | 18 (16, 22) | 20 (17, 24) | −5.47 | < 0.001 |
| TP (g/L) | 73 (70.7, 75.3) | 74.1 (71.7, 76.5) | −3.93 | < 0.001 |
| TBIL (μmol/L) | 9.97 (7.85, 13.57) | 10.875 (8.67, 13.78) | −2.25 | 0.03 |
| eGFR (ml/min) | 105.7261 (98.49, 109.27) | 92.9344 (81.88, 99.67) | −14.26 | < 0.001 |
| T2DM n (%) | 25 (12.1) | 586 (19.4) | 6.775 | 0.008 |
| Smoking n (%) | 4 (1.9) | 42 (1.4) | 0.40 | 0.53 |
| Drinking n (%) | 6 (2.9) | 34 (1.1) | 4.97 | 0.03 |
| History of Hypertension n (%) | 25 (12.1) | 1044 (34.6) | 44.24 | < 0.001 |
| History of CHD n (%) | 6 (2.9) | 169 (5.6) | 2.75 | 0.97 |
| History of sleep disorders n (%) | 3 (1.4) | 99 (3.3) | 2.12 | 0.15 |
Data are presented as the mean ± SD, number (as %), or median (range), as appropriate. Comparisons between the three groups were made using ANOVA or Fisher’s exact test, as appropriate. International system of units (SI) conversion: BMI body mass index, CHD Coronary heart disease, SBP systolic blood pressure, DBP diastolic blood pressure, TC total cholesterol, TG triglycerides, UA uric acid, BUN blood urea nitrogen, CREA serum creatinine, e-GFR estimated glomerular filtration rate, FPG fasting plasma glucose, HDL-c high-density lipoprotein cholesterol, LDL-c low-density lipoprotein cholesterol, TP Total Protein