Table 2.
Baseline comparison of relevant indexes before and after menopause
| Premenopausal | t/Z/χ 2 | P | Postmenopausal | t/Z/χ 2 | P | |||
|---|---|---|---|---|---|---|---|---|
| Non-diabetic (n = 182) |
Diabetic (n = 25) |
Non-diabetic (n = 586) |
Diabetic (n = 2434) |
|||||
| Age (years) | 46.65 ± 1.83 | 46.68 ± 1.38 | 0.083 | 0.934 | 60.05 ± 7.39 | 62.93 ± 7.75 | 8.158 | < 0.001 |
| BMI (kg/m2) | 23.83 (21.975, 25.79) | 24.91 (23.05, 27.78) | −1.896 | 0.058 | 24.27 (22.22,26.31) | 25.39 (23.03, 27.99) | −7.181 | < 0.001 |
| WC (cm) | 78 (73, 81) | 81 (78, 90.5) | −2.553 | 0.011 | 81 (77, 84.25) | 84 (80, 91) | −10.08 | < 0.001 |
| SBP (mmHg) | 127.5 (120, 136.25) | 130 (119.5, 162.5) | −1.324 | 0.185 | 134 (123, 149) | 140 (130, 158.25) | −7.422 | < 0.001 |
| DBP (mmHg) | 79 (70, 85) | 85 (72.5, 92) | −1.616 | 0.106 | 81 (74, 90) | 84 (76, 93.25) | −3.258 | 0.001 |
| HbA1c (%) | 5.4 (5.1, 5.7) | 6.4 (5.6, 8.7) | −5.001 | < 0.001 | 5.6 (5.3, 5.9) | 6.8 (6.1, 7.8) | −29.113 | < 0.001 |
| FPG (mmol/L) | 5.18 (4.88, 5.48) | 5.43 (5.06, 8.52) | −2.949 | 0.003 | 5.35 (5.06, 5.74) | 6.975 (5.67, 8.53) | −23.812 | < 0.001 |
| TC (mmol/L) | 4.735 (4.21, 5.36) | 4.51 (4.15, 5.6) | −0.429 | 0.668 | 5.24 (4.68, 5.8) | 5.2 (4.63, 5.88) | −0.014 | 0.989 |
| TG (mmol/L) | 1.465 (1.12, 1.99) | 1.55 (1.17, 2.17) | −0.815 | 0.415 | 1.73 (1.37, 2.28) | 1.92 (1.5, 2.61) | −5.974 | < 0.001 |
| LDL-C (mmol/L) | 2.445 (2.09, 2.76) | 2.32 (1.915, 3.14) | −0.249 | 0.803 | 2.73 (2.31, 3.2) | 2.75 (2.28, 3.2) | −0.010 | 0.992 |
| UA (μmol/L) | 236.8 (203.18,267.13) | 227.8 (197.4, 269.7) | −0.274 | 0.784 | 251.9 (213.3294.5) | 261.05 (218.5324.3) | −3.537 | < 0.001 |
| BUN (mg/dl) | 4.405 (3.73, 5.22) | 4.91 (3.75, 6.34) | −1.472 | 0.141 | 4.93 (4.21, 5.77) | 5.055 (4.37, 6.01) | −2.808 | 0.005 |
| ALT (U/L) | 18 (14, 25) | 19 (14, 25) | −0.483 | 0.629 | 20 (16, 25) | 22 (18, 29) | −6.021 | < 0.001 |
| AST (U/L) | 18 (15.75, 23) | 16 (15.5, 21.5) | −0.662 | 0.508 | 20 (18, 24) | 20 (17, 24) | −0.491 | 0.623 |
| TP (g/L) | 72.8 (70.6, 75) | 75 (73.15, 77.55) | −3.084 | 0.002 | 74 (71.6, 76.3) | 74.4 (72.2, 77) | −3.131 | 0.002 |
| TBIL (μmol/L) | 9.995 (7.84, 13.59) | 9.15 (7.81, 13.56) | −0.564 | 0.572 | 10.845 (8.66,13.69) | 10.99 (8.68, 14.03) | −0.620 | 0.535 |
| eGFR (ml/min) | 105.48 (97.45,108.81) | 108.13 (98.56,111.67) | −1.718 | 0.086 | 92.93 (82.12,99.73) | 92.66 (79.75, 99.41) | −1.068 | 0.286 |
| Smoking n (%) | 4 (2.2) | 0 (0) | 0.560 | 0.454 | 34 (1.4) | 8 (1.4) | 0.003 | 0.953 |
| Drinking n (%) | 4 (2.2) | 2 (8) | 2.630 | 0.105 | 32 (1.3) | 2 (0.3) | 4.020 | 0.045 |
| History of Hypertension n (%) | 17 (9.3) | 8 (32) | 10.630 | 0.001 | 751 (20.9) | 293 (50) | 76.536 | < 0.001 |
| History of CHD n (%) | 4 (2.2) | 2 (8) | 2.630 | 0.110 | 115 (4.7) | 54 (9.2) | 18.030 | < 0.001 |
| History of sleep disorders n (%) | 3 (1.6) | 0 (0) | 0.420 | 0.520 | 68 (2.8) | 31 (5.3) | 9.283 | 0.002 |
Data are presented as the mean ± SD, number (as %), or median (range), as appropriate. Comparisons between the three groups were made using ANOVA or Fisher’s exact test, as appropriate International system of units (SI) conversion: BMI body mass index, CHD Coronary heart disease, SBP systolic blood pressure, DBP diastolic blood pressure, TC total cholesterol, TG triglycerides, UA uric acid, BUN blood urea nitrogen, e-GFR estimated glomerular filtration rate, FPG fasting plasma glucose, LDL-C low-density lipoprotein cholesterol, TBIL Total bilirubin, TP Total Protein