Fig. 3.

Effects of MFR and PPD on CI-induced rhabdomyolysis. At the end of resuscitation, we measured serum K⁺ levels (a), myoglobin concentrations (b), and CK activities (c) to evaluate rhabdomyolysis. To evaluate the clearance ability of different interventions, removal rates of serum K⁺ (d), myoglobin (e) and CK (f) were calculated. Dialysis fluids were collected for the measurements of K⁺ (g), myoglobin (h) levels and CK activities (i). In each group, the number of animals was ≥5 at all time points. Con = control group; MFR = massive fluid resuscitation; PPD = preventive peritoneal dialysis. In each group, number of animals ≥5. ^*p < 0.05, ^** p < 0.01, ^*** p < 0.001 vs. CP group; ^#p < 0.05, ^##p < 0.01, ^###p < 0.001 vs. MFR group. ^∇∇ p < 0.01 vs. PPD group