Table 1.
Part of plant used | MEAN IC50 ±SEM (μg/ml) | SI | |||||
---|---|---|---|---|---|---|---|
Jurkat | T. brucei | L. donovani | P. falciparum | T. brucei | L. donovani | P. falciparum | |
Root | 247.16±0.05 | 3.41±0.03 | 45.2±0.10 | 334.77±0.02 | 72.48 | 12.91 | 0.74 |
Stem bark | 583.53±0.02 | 39.43±0.04 | 13.5±0.04 | 112.15±0.01 | 6.27 | 18.30 | 5.20 |
Leaves | 95.83±0.15 | 27.73±0.02 | >1000±0.12 | >1000±0.15 | 3.46 | <0.10 | <0.96 |
Mean IC50 and standard errors (SE) were calculated from three distinct experiments. Selectivity index (SI) was calculated as the ratio of IC50 in Jurkat to IC50 in the respective parasite.