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. 2019 Jul 15;47(9):2188–2199. doi: 10.1177/0363546519855645

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© 2019 The Author(s)

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (https://www.creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 6. — Gene expression of fibrin + cells group cultured under 3 mechanical loading conditions. Gene expression was analyzed by quantitative reverse-transcription polymerase chain reaction for (A) SOX9, (B) COL2A1, (C) ACAN, (D) COL2:COL1 (ratio of collagen type II to collagen type I), (E) MMP3, and (F) ADAMTS5. All expression levels are expressed relative to day 0 controls. *Comparison with day 0 controls (P < .05). **Comparison with other time points within the same activation group (P < .05). ^#Comparison between activation groups at the same time point (P < .05). ACAN, aggrecan; ADAMTS, a disintegrin and metalloproteinase with thrombospondin motifs; COL1A1, collagen type I α1; MMP, matrix metalloproteinase; SOX9, SRY-related HGMG box containing gene 9.