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. 2019 Jul 11;10:1469. doi: 10.3389/fmicb.2019.01469

Figure 2.

Figure 2

Effect of IY, GI, or G 250 treatment on tongue fungal burden and histological inflammation. (A) Fungal burden of mice treated with 10 μl of saline, FLZ (4 mg/ml), IY, GI, or G 250 (all 100 mg/ml) was evaluated by CFU count at days +3, +6, and +8 post-infection in tongue of infected mice. Data are from two different experiments each with n = 3 mice/group. The boxplot graphics show median including the 25th and 75th percentile. #p < 0.05 FLZ or compound-treated infected mice vs. saline-treated infected mice. (B) Tongue sections from uninfected and infected mice treated with 10 μl of saline, FLZ (4 mg/ml), IY, GI, and G 250 (all 100 mg/ml) are shown (day +8 post-infection). Images (Bar = 200 μm, magnification 10×) are representative of two separate experiments with similar results.