Figure 4.

Ex vivo imaging of mice orally infected with BLI-C. albicans and treated with FLZ, IY, or GI. Ex vivo analysis of esophagus, stomach, feces, kidneys and liver from saline, FLZ, IY or GI-treated infected mice are shown. Briefly, 8 days post-infection mice were euthanized, and esophagus, stomach, kidneys, liver and feces were recovered and then soaked with 10 μl of coelenterazine (0.5 mg/ml) to detect the C. albicans burden using the Lumina XRMS Imaging system. Data are from one representative mouse from one experiment. Region Of Interest (ROI) was quantified with Living Image R software package.