Figure 6.

A hypothetical model depicting how RipAB suppresses immunity via the down‐regulation of calcium signalling. RipAB could bind directly to the DNA to impede transcription or could interact with Ca²⁺ signalling regulators or transcription factors (TF). Down‐regulation of the Ca²⁺ transport channel gene CNGC would affect Ca²⁺ influx, and down‐regulation of the calcium sensor would result in the inability of Ca²⁺ perception, which would lead to the inactivation of downstream immune responses. CaM/CML, Calmodulin; CDPK, calcium‐dependent protein kinase; CNGC, cyclic nucleotide‐gated ion channel; NO, nitric oxide; RBOH, respiratory burst oxidase homologue; ROS, reactive oxygen species.