Table 2:

Linear regression summary statistics for the association of SCARB1 SNP rs10846744 and log CCIMT by MESA racial/ethnic group and in meta-analysis, under multiple models of adjustment.

		Model 1				Model 2
Group	Allele frequency	N	Beta	SE	P-value	N	Beta	SE	P-value
Caucasian	0.82	2405	−0.011	0.007	0.092	2367	−0.010	0.007	0.115
Chinese	0.43	701	−0.017	0.010	0.098	687	−0.019	0.010	0.056
African American	0.38	2457	−0.009	0.005	0.102	2425	−0.007	0.005	0.206
Hispanic	0.65	2050	−0.018	0.006	0.005	2001	−0.015	0.006	0.016
Meta-analysis			−0.013	0.003	1.07E-04		−0.011	0.003	5.61E-04

Allele frequencies and estimated effects are reported for the effect allele G (versus the reference allele C). Model 1 includes adjustment for age, sex, study site, and principal components of ancestry. Model 2 includes all covariates in Model 1, with the addition of HDL-C, LDL-C, triglycerides, BMI, fasting glucose, and hypertension status. Estimated effect sizes are presented based on an additive genetic model with 1 degree of freedom, for the log-transformed phenotype common IMT (mm).