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. Author manuscript; available in PMC: 2020 Jun 4.
Published in final edited form as: J Am Coll Cardiol. 2019 Jun 4;73(21):2722–2737. doi: 10.1016/j.jacc.2019.03.476

Figure 1. Assessment of e-liquid flavor-induced cytotoxicity in iPSC-ECs.

Figure 1.

Effects of 6 e-liquid flavors with different nicotine concentrations on iPSC-EC viability after 48-hour treatment were determined using a luminescent CellTiter-Glo 2.0 assay. The data were obtained using iPSC-ECs from 3 biological donors and the assay was repeated twice. Data are represented as mean ± SD. ap < 0.05, compared to controls within 0 mg nicotine/ml group; bp < 0.05, compared to controls within 6 mg nicotine/ml group; cp < 0.05, compared to control within 18 mg nicotine/ml group. Statistically significant from controls (Bonferroni-adjusted P<0.05). VG: vegetable glycerin; PG: propylene glycol.