Figure 2.

Potential targets of helper component proteinase (HCPro) in the antiviral RNA silencing pathway. Simplified schematic representation of the RNA silencing‐mediated defences in plants that are deployed against RNA viruses. Steps of the cascade at which HCPro from different potyvirids may be acting in order to block this defensive response are indicated. AGO, Argonaute protein; DCL, Dicer‐like protein; DRB, double‐stranded RNA‐binding protein; HEN1, HUA enhancer 1; RDR, RNA‐dependent RNA polymerase; RISC, RNA‐induced silencing complex; SGS3, supressor of gene silencing 3.