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. 2011 Sep 23;13(3):276–287. doi: 10.1111/j.1364-3703.2011.00744.x

Figure 5.

Figure 5

Comparison of unique splicing factor (SF) binding motifs between the two haplotypes in the second intron region, the hotspot Z in the leucine‐rich repeat (LRR) domain. Arrows mark mutations forming SF binding motifs. Numbers above/below the arrows are the splicing factors binding motifs 1 (CUG‐BP), 2 (hnRNPA1), 3 (hnRNPH/F) and 4 (PTB) (Akerman et al., 2009). Boxes with diagonal hatching are exons. Box with vertical hatching is the retained intron. Broken thick line is the spliced intron. (a) Nonsplicing haplotype. (b) Alternative splicing haplotype. nt, nucleotides.