Table 2. The odds ratios of high blood pressure at age of 7 years with different concentrations of total serum bilirubin at 48h after birth.
Total serum bilirubin | High blood pressure at 7 years old | |||||||
---|---|---|---|---|---|---|---|---|
n/N (%) | Model 1 | Model 2 | Model 3 | |||||
OR | 95% CI | OR | 95% CI | OR | 95% CI | |||
Preterm Infants | < 3mg/dl | 55/613 (9.0) | 1 | 1 | 1 | |||
≥ 3mg/dl, < 6mg/dl | 148/1270 (11.7) | 1.34 | 0.97, 1.85 | 1.36 | 0.98, 1.89 | 1.36 | 0.98, 1.91 | |
≥ 6mg/dl, < 9mg/dl | 202/1711 (11.8) | 1.36 | 0.99, 1.86 | 1.35 | 0.98, 1.85 | 1.36 | 0.99, 1.86 | |
≥ 9mg/dl, < 12mg/dl | 136/951 (14.3) | 1.69 | 1.22, 2.36 | 1.55 | 1.10, 2.19 | 1.54 | 1.09, 2.21 | |
≥ 12mg/dl | 169/1180 (14.3) | 1.70 | 1.23, 2.34 | 1.42 | 1.01, 2.00 | 1.42 | 1.00, 2.02 | |
Term Infants | < 3mg/dl | 744/6452 (11.5) | 1 | 1 | 1 | |||
≥ 3mg/dl, < 6mg/dl | 1197/10510 (11.4) | 0.99 | 0.90, 1.09 | 1.00 | 0.91, 1.11 | 1.01 | 0.91, 1.12 | |
≥ 6mg/dl, < 9mg/dl | 1005/9248 (10.9) | 0.94 | 0.85, 1.03 | 0.97 | 0.88, 1.08 | 0.96 | 0.85, 1.07 | |
≥ 9mg/dl, < 12mg/dl | 392/3315 (11.8) | 1.03 | 0.90, 1.17 | 1.07 | 0.93, 1.22 | 1.07 | 0.91, 1.25 | |
≥ 12mg/dl | 226/2294 (11.6) | 1.01 | 0.87, 1.17 | 1.02 | 0.88, 1.19 | 1.00 | 0.85, 1.24 |
Model 1: crude odds ratios; Model 2: Adjusted for race (white, black, and other race), sex (male and female), birth weight (< 2500g, 2500g–4000g and ≥4000g), gestational age (as a categorical variable), transfusion (yes and no), hypertensive disorders during pregnancy (none, moderate, and severe), maternal smoking (0, 1–19 and 20 cigarette per day during pregnancy) and socioeconomic status (comprised of 5 categories as assessed by the original CPP investigators); Model 3: adjusted for the same factors as model 2 in Generalized Estimating Equation mode