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. Author manuscript; available in PMC: 2020 Apr 10.
Published in final edited form as: J Am Chem Soc. 2019 Mar 26;141(14):5692–5698. doi: 10.1021/jacs.8b09665

Figure 1.

Figure 1.

(A) PreQ1-RS riboswitch secondary structure in the unbound and bound state. (B) The bound tertiary structure of PreQ1-RS (PDB 2L1 V) with sites of BFU fluorophore insertion (U9-red, U11-blue, U14-green) and PreQ1 ligand (orange).8