Table 1.
Characteristic | No. | % |
---|---|---|
25(OH)D, ng/mL, mean (SD) | 21.0(10.2) | |
Age, years, mean (SD) | 60(11) | |
Sex | ||
Female | 215 | 41.0 |
Male | 309 | 59.0 |
Race/ethnicity | ||
White | 450 | 85.9 |
Black | 38 | 7.3 |
Other | 31 | 5.9 |
Unknown/missing | 5 | 0.9 |
ECOG performance statusb | ||
0–1 | 500 | 95.4 |
2 | 24 | 4.6 |
No. of metastatic sites, median (range) | 2(1–4) | |
Liver-only metastasis | ||
Yes | 127 | 24.2 |
No | 397 | 75.8 |
One metastatic site, not including liver | ||
Yes | 38 | 7.3 |
No | 486 | 92.7 |
Multiple metastatic sites, not including liver | ||
Yes | 62 | 11.8 |
No | 462 | 88.2 |
Prior adjuvant therapy | ||
Yes | 78 | 14.9 |
No | 415 | 79.2 |
Missing | 31 | 5.9 |
Treatment arm | ||
IFL | 114 | 21.8 |
FOLFOX | 307 | 58.6 |
IROX | 103 | 19.7 |
Season of blood collection | ||
Summer (June, July, August) | 135 | 27.4 |
Fall (September, October, November) | 78 | 15.8 |
Winter (December, January, February) | 133 | 27.0 |
Spring (March, April, May) | 147 | 29.8 |
Missing | 31 | 5.9 |
Geographic region of registering sitec | ||
Midwestern US | 228 | 43.5 |
Northeastern US and Canada | 114 | 21.8 |
Southern US and Puerto Rico | 85 | 16.2 |
Western US | 56 | 10.7 |
Missing | 41 | 7.8 |
25(OH)D 25-hydroxyvitamin D3, ECOG Eastern Cooperative Oncology Group, FOLFOX fluorouracil, leucovorin, oxaliplatin, IFL irinotecan, bolus fluorouracil, leucovorin, IROX irinotecan, oxaliplatin, SD standard deviation
Baseline information available for 524 patients
Grade 0 = fully active, able to carry on all pre-disease performance without restriction; grade 1 = restricted in physically strenuous activity but ambulatory and able to carry out work of a light or sedentary nature, e.g., light house work, office work; grade 2 = ambulatory and capable of all selfcare but unable to carry out any work activities, up and about more than 50% of waking hours
Defined according to the US Census Bureau: Midwest = IL, IN, IA, KS, MI, MN, MO, NE, ND, OH, SD, WI; Northeast = CT, ME, MA, NH, NJ, NY, PA, RI, VT; South = AL, DE, FL, GA, KY, LA, MD, NC, OK, SC, TN, TX, VA, WV; West = AZ, CA, CO, HI, ID, MT, NV, NM, OR, UT, WA, WY