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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Cancer Causes Control. 2019 May 18;30(7):757–765. doi: 10.1007/s10552-019-01183-1

Table 1.

Baseline characteristics of patients with metastatic colorectal cancera

Characteristic No. %
25(OH)D, ng/mL, mean (SD) 21.0(10.2)
Age, years, mean (SD) 60(11)
Sex
 Female 215 41.0
 Male 309 59.0
Race/ethnicity
 White 450 85.9
 Black 38 7.3
 Other 31 5.9
 Unknown/missing 5 0.9
ECOG performance statusb
 0–1 500 95.4
 2 24 4.6
No. of metastatic sites, median (range) 2(1–4)
Liver-only metastasis
 Yes 127 24.2
 No 397 75.8
One metastatic site, not including liver
 Yes 38 7.3
 No 486 92.7
Multiple metastatic sites, not including liver
 Yes 62 11.8
 No 462 88.2
Prior adjuvant therapy
 Yes 78 14.9
 No 415 79.2
 Missing 31 5.9
Treatment arm
 IFL 114 21.8
 FOLFOX 307 58.6
 IROX 103 19.7
Season of blood collection
 Summer (June, July, August) 135 27.4
 Fall (September, October, November) 78 15.8
 Winter (December, January, February) 133 27.0
 Spring (March, April, May) 147 29.8
 Missing 31 5.9
Geographic region of registering sitec
 Midwestern US 228 43.5
 Northeastern US and Canada 114 21.8
 Southern US and Puerto Rico 85 16.2
 Western US 56 10.7
 Missing 41 7.8

25(OH)D 25-hydroxyvitamin D3, ECOG Eastern Cooperative Oncology Group, FOLFOX fluorouracil, leucovorin, oxaliplatin, IFL irinotecan, bolus fluorouracil, leucovorin, IROX irinotecan, oxaliplatin, SD standard deviation

a

Baseline information available for 524 patients

b

Grade 0 = fully active, able to carry on all pre-disease performance without restriction; grade 1 = restricted in physically strenuous activity but ambulatory and able to carry out work of a light or sedentary nature, e.g., light house work, office work; grade 2 = ambulatory and capable of all selfcare but unable to carry out any work activities, up and about more than 50% of waking hours

c

Defined according to the US Census Bureau: Midwest = IL, IN, IA, KS, MI, MN, MO, NE, ND, OH, SD, WI; Northeast = CT, ME, MA, NH, NJ, NY, PA, RI, VT; South = AL, DE, FL, GA, KY, LA, MD, NC, OK, SC, TN, TX, VA, WV; West = AZ, CA, CO, HI, ID, MT, NV, NM, OR, UT, WA, WY

HHS Vulnerability Disclosure