Skip to main content
. 2019 Jul 8;8:e46156. doi: 10.7554/eLife.46156

Table 5. Summary of relationships between memory impairment and structural/functional abnormalities across patients.

Memory composite score Effects of HPC atrophy
Anterograde retrieval Verbal recognition Does not explain additional variance beyond that explained by inter-HPC rsFC reduction
Visual Recognition Fully mediated by PCC rsALFF reduction
Verbal Recall
Visual Recall
Anterograde Retention (Visual Forgetting) Direct effect - not mediated by extra-HPC abnormalities
Remote Autobiographical Memory Fully mediated by thalamic volume reduction

HPC: hippocampus; PCC: posterior cingulate cortex; rsALFF: resting-state amplitude of low frequency fluctuations; rsFC: resting-state functional connectivity.