Table 1.
Baseline population characteristics
| Characteristics | FIGHTDIGO Population (n=201) | Patients with at least one assessable CT scan (n=150) | No assessable CT scan (n=51) | Univariate Analysis P value |
|---|---|---|---|---|
| Age, mean ± SD | 65.5 ± 10.8 | 65.6 ± 10.9 | 65.1 ± 10.8 | 0.80 |
| Gender, N (%) | 0.92 | |||
| Men | 117 (58.2) | 87 (58.0) | 30 (58.8) | |
| Women | 82 (41.8) | 63 (42.0) | 21 (41.2) | |
| BMI, mean ±SD | 25.0 ± 5.1 | 24.9 ± 4.9 | 25.3 ± 5.5 | 0.56 |
| Leg edema, N (%) | 4 (2.0) | 4 (2.7) | 0 (0.0) | 0.57 |
| Serum albumin, mean ±SD | 38.6 ± 4.5 | 38.4 ± 4.6 | 39.4 ± 4.1 | 0.15 |
| C‐reactive protein, mean ±SD | 15.9 ± 32.8 | 17.8 ± 37.1 | 11.1 ± 15.5 | 0.09 |
| Previous oncologic surgery, N (%) | 128 (63.7) | 87 (58.0) | 41 (80.4) | 0.004 |
| mGPS, N (%) | 0.29 | |||
| 0 | 99 (55.0) | 68 (51.5) | 31 (64.6) | |
| 1 | 68 (37.8) | 54 (40.9) | 14 (29.2) | |
| 2 | 13 (7.2) | 10 (7.6) | 2 (6.2) | |
| G8 score, mean ± SD | 12.4 ± 2.1 | 12.1 ± 2.6 | 13.2 ± 2.2 | 0.12 |
| Primary tumor, N (%) | 0.35 | |||
| Colon and rectum | 103 (51.2) | 71 (47.3) | 32 (62.7) | |
| Oesphagus | 8 (4.0) | 5 (3.3) | 3 (5.9) | |
| Stomach | 22 (10.9) | 16 (10.7) | 6 (11.8) | |
| Cholangiocarcinoma | 11 (5.5) | 9 (6.0) | 2 (3.9) | |
| Pancreas | 44 (21.9) | 38 (25.3) | 6 (11.8) | |
| Small intestine | 3 (1.5) | 2 (1.3) | 1 (2.0) | |
| Neuroendocrine tumor | 8 (4.0) | 7 (4.7) | 1 (2.0) | |
| Adenocarcinoma, unknown primitive tumor | 2 (1.0) | 2 (1.3) | 0 (0.0) | |
| Stage, N (%) | <0.0001 | |||
| Local | 40 (19.9) | 19 (12.7) | 19 (41.2) | |
| Locally advanced | 23 (11.4) | 16 (10.7) | 7 (13.7) | |
| Metastatic | 138 (68.7) | 115 (76.7) | 23 (45.1) | |
| Type of treatment, N (%) | 0.004 | |||
| Chemotherapy alone | 147 (73.1) | 101 (67.3) | 46 (90.2) | |
| Biotherapy alone | 4 (2.0) | 4 (2.7) | 0 (0.0) | |
| Chemotherapy and biotherapy | 50 (24.9) | 45 (30.0) | 5 (9.8) | |
| Indication, N (%) | <0.0001 | |||
| Adjuvant | 47 (23.4) | 23 (15.3) | 24 (47.1) | |
| Neoadjuvant | 10 (5.0) | 7 (4.7) | 3 (5.9) | |
| Palliative | 144 (71.6) | 120 (80.0) | 24 (47.1) | |
| First line, N (%) | 132 (65.2) | 92 (61.3) | 40 (78.4) | 0.03 |
Abbreviations: BMI, body mass index; mGPS, modified Glasgow Prognostic Score; N, number; SD, standard deviation.