Table 3.
Correlation between clinicopathological features and mutational status
| Mutation of WNT pathway | Mutation of RTK‐RAS pathway | Mutation of PI3K pathway | Mutation of TGF‐β pathway | Mutation of P53 pathway | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No | Yes | Total | P‐Value | No | Yes | Total | P‐Value | No | Yes | Total | P‐Value | No | Yes | Total | P‐Value | No | Yes | Total | P‐Value | ||
| Gender | F | 3 | 9 | 12 | 1.000 | 7 | 5 | 12 | 1.000 | 10 | 2 | 12 | 1.000 | 11 | 1 | 12 | 0.370 | 4 | 8 | 12 | 0.471 |
| M | 4 | 16 | 20 | 12 | 8 | 20 | 17 | 3 | 20 | 15 | 5 | 20 | 10 | 10 | 20 | ||||||
| Age | <62 | 3 | 13 | 16 | 1.000 | 10 | 6 | 16 | 1.000 | 15 | 1 | 16 | 0.333 | 13 | 3 | 16 | 1.000 | 5 | 11 | 16 | 0.285 |
| ≥62 | 4 | 12 | 16 | 9 | 7 | 16 | 12 | 4 | 16 | 13 | 3 | 16 | 9 | 7 | 16 | ||||||
| Tumor Size | ≤4 cm | 3 | 16 | 19 | 0.401 | 8 | 11 | 19 | 0.028 | 17 | 2 | 19 | 0.375 | 15 | 4 | 19 | 1.000 | 10 | 9 | 19 | 0.289 |
| >4 cm | 4 | 9 | 13 | 11 | 2 | 13 | 10 | 3 | 13 | 11 | 2 | 13 | 4 | 9 | 13 | ||||||
| Stage | I, II | 3 | 16 | 19 | 0.384 | 12 | 7 | 19 | 1.000 | 15 | 4 | 19 | 0.624 | 16 | 3 | 19 | 0.653 | 7 | 12 | 19 | 0.710 |
| III, IV | 4 | 8 | 12 | 7 | 5 | 12 | 11 | 1 | 12 | 9 | 3 | 12 | 6 | 6 | 12 | ||||||
| Site | Rectum | 3 | 5 | 8 | 0.327 | 5 | 3 | 8 | 1.000 | 6 | 2 | 8 | 0.578 | 8 | 0 | 8 | 0.296 | 4 | 4 | 8 | 0.704 |
| Colon | 4 | 20 | 24 | 14 | 10 | 24 | 21 | 3 | 24 | 18 | 6 | 24 | 10 | 14 | 24 | ||||||
| LN metastasis | − | 3 | 16 | 19 | 0.401 | 12 | 7 | 19 | 0.720 | 15 | 4 | 19 | 0.625 | 16 | 3 | 19 | 0.666 | 7 | 12 | 19 | 0.473 |
| + | 4 | 9 | 13 | 7 | 6 | 13 | 12 | 1 | 13 | 10 | 3 | 13 | 7 | 6 | 13 | ||||||
P‐Value by Fisher's Exact Test.