Table 2.
Co‐occurring point mutations in genes in the Ras/Raf pathway with TP53 mutations
Individual ID | TP53 mutation | VAF (TP53) | KRAS mutation | VAF (KRAS) | NRAS mutation | VAF (NRAS) | BRAF mutation | VAF (BRAF) |
---|---|---|---|---|---|---|---|---|
Pt9 | c.782 + 1G > A | 0.44 | p.G12V | 0.50 | ||||
Pt13 | p.R248W | 0.06 | p.G12D | 0.01 | ||||
p.Y205C | 0.01 | |||||||
Pt14 | p.M243_G244del | 0.43 | p.A59G | 0.17 | ||||
Pt43 | P.N239* | 0.26 | p.G12V | 0.42 | ||||
Pt69 | p.C277F | 0.57 | p.G12A | 0.34 | ||||
Pt30 | p.P64Afs*85 | 0.41 | p.Q61R | 0.42 | ||||
Pt51 | p.R342* | 0.15 | p.G12C | 0.12 | ||||
Pt59 | p.R273H | 0.87 | p.Q61K | 0.41 | ||||
Pt36 | c.920‐2A > G | 0.67 | p.D594N | 0.37 |