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IC50 values of AZD6738 in BTC cell lines
| Cell line | IC50 (μM) |
|
|---|---|---|
| MTT | CFA | |
| SNU245 | 4.57 | 0.87 |
| SNU308 | 3.28 | 0.28 |
| SNU478 | 0.46 | 0.1 |
| SNU869 | 0.44 | 0.13 |
| SNU1079 | 2.76 | 0.4 |
| SNU1196 | 1.21 | 0.6 |
| HuCCT-1 | 3.23 | 0.5 |
| TFK-1 | 1.12 | 0.38 |
| SNU2670 | > 10 | 0.9 |
IC50, the half maximal inhibitory concentration; BTC, biliary tract cancer; MTT, 3-(4,5-dimethylthiazol-2yl)-2, 5-diphenyltetrazolium bromide; CFA, colony-forming assay.
