Table 1.
Baseline patient characteristics
| Characteristic | No. (%) (n=60) |
|---|---|
| Age, median (range, yr) | 57 (27-74) |
| Sex | |
| Male | 35 (58.3) |
| Female | 25 (41.7) |
| ECOG PS | |
| 0 | 15 (25.0) |
| 1 | 45 (75.0) |
| Histology of adenocarcinoma | |
| Well differentiated | 16 (26.7) |
| Moderately differentiated | 37 (61.7) |
| Mucinous adenocarcinoma | 1 (1.7) |
| Poorly differentiated | 6 (10.0) |
| B-Raf status | |
| Wild type | 45 (75.0) |
| Mutated | 8 (13.3) |
| Unknown | 7 (11.7) |
| K-Ras status | |
| Wild type | 39 (65.0) |
| Mutated | 16 (26.7) |
| Unknown | 5 (8.3) |
| Localization of the primary tumor | |
| Right side colon | 15 (25.0) |
| Left side colon | 45 (75.0) |
| State at study enrollment | |
| Recurrence | 20 (33.3) |
| Locally advanced and distant metastasis | 40 (66.7) |
| Site of distant metastasis | |
| Liver | 49 (81.7) |
| Lung | 22 (36.7) |
| Lymph nodes | 16 (26.7) |
| Peritoneal seeding | 8 (13.3) |
| Bone | 3 (5.0) |
ECOG PS, Eastern Cooperative Oncology Group performance status.