FIG 7.

Protection from intravenous SIVmac239 challenge following infusion with CD8β255R1. At 4 weeks after infusion with CD8β255R1 or control IgG, animals were challenged intravenously with SIVmac239. Viral load assays were performed for full-length nef (red, open symbols) and Δnef (red, closed symbols) at the indicated time points for each animal and graphed in the context of absolute CD8αβ⁺ T cell count (black). The limit of detection for the assay (100 vRNA copies/ml) is represented by a horizontal red dotted line. Animals with identifications highlighted in red became infected following SIVmac239 challenge. *, cy0690 required necropsy at week 6 following CD8β255R1 infusion.