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Quantification of SIV DNA and SIV RNA from tissue samples. Cellular DNA and RNA were extracted from spleen, lung, and PBMCs from seven SIV-infected ART-suppressed macaques. SIV gag DNA (left) and SIV gag RNA (right) were measured by ddPCR, with the limit of quantitation (LOQ, dashed lines) being 1 copy per reaction mixture. Open symbols indicate animals that were treated with LRAs in vivo; closed symbols indicate animals that were not treated with LRAs.
