FIG 7.

Functional latent reservoirs are detected in both CD4⁺ T cells and monocytes/macrophages isolated from SIV-infected ART-suppressed animal tissues. The frequency of latently infected CD4⁺ T cells (left) and monocytes/macrophages (right) isolated from the spleen, lung, and PBMCs of suppressed ART-treated macaques were quantitated by cell-specific QVOAs. The horizontal black lines represent the median number of infectious units per million cells (IUPM), and each symbol represents an animal. Open symbols indicate animals that were treated with LRAs in vivo; closed symbols indicate animals that were not treated with LRAs. LOD, limit of detection.