Table 1.
Results of the meta-analysis of resting-state functional connectivity in patients with schizophrenia.
| Seed networks | Effect (threshold) | Effect anatomy | Coordinates | Voxels | Max. P | P | ||
|---|---|---|---|---|---|---|---|---|
| x | y | z | ||||||
| AN | SZ < HC (eb) | Left insula | −42 | 0 | 4 | 7,234 | 0.29 | <0.05 |
| CN | SZ < HC (eb) | Right superior temporal cortex | 42 | 8 | −6 | 1,987 | 0.22 | <0.01 |
| DMN | SZ < HC (hb) | Right medial prefrontal cortex | 2 | 52 | 2 | 103 | 0.26 | <0.05 |
| SZ < HC (eb) | Left precuneus | −2 | −68 | 32 | 2,282 | 0.16 | <0.01 | |
| SZ < HC (eb) | Left anterior cingulate cortex | 0 | 36 | 22 | 5,648 | 0.17 | <0.05 | |
| SRN | SZ < HC (eb) | Right superior temporal cortex | 48 | 8 | −4 | 2,463 | 0.20 | <0.01 |
| SMN | SZ < HC (eb) | Right precentral gyrus | 50 | −6 | 36 | 1,682 | 0.25 | <0.05 |
AN, auditory network; CN, core network; DMN, default mode network; SRN, self-referential network; SMN, somatomotor network; SZ, schizophrenia; HC, healthy control; eb, extent-based; hb, height-based; Max. P, maximum P value.
The coordinates are from the Montreal Neurological Institute space. Voxels represent the sum of 1 × 1 × 1 mm3 voxels. Max. P is the maximum statistic of the studies presenting the peak effect weighted mainly by sample size. All the results are significant at p < 0.05 or < .01, corrected for familywise error rate.